RESISTANCE IS NOT FUTILE: THE ROLE OF QUORUM SENSING PLASTICITY IN PSEUDOMONAS AERUGINOSA INFECTIONS AND ITS LINK TO INTRINSIC MECHANISMS OF ANTIBIOTIC RESISTANCE

Resistance Is Not Futile: The Role of Quorum Sensing Plasticity in Pseudomonas aeruginosa Infections and Its Link to Intrinsic Mechanisms of Antibiotic Resistance

Bacteria use a cell-cell communication process called quorum sensing (QS) to orchestrate collective behaviors.QS relies on the group-wide detection of extracellular signal molecules called autoinducers (AI).Quorum sensing is required for virulence and biofilm formation in the human pathogen Pseudomonas aeruginosa.In P.aeruginosa, LasR and RhlR are

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